1 / 1 DeCS    
Descritor Inglês:   Omalizumab 
Descritor Espanhol:   Omalizumab 
Descritor Português:   Omalizumab 
Sinônimos Português:   Omalizumabe
Xolair  
Categoria:   D12.776.124.486.485.114.071.500
D12.776.124.486.485.114.224.060.844
D12.776.124.790.651.114.071.500
D12.776.124.790.651.114.224.060.844
D12.776.377.715.548.114.071.500
D12.776.377.715.548.114.224.200.844
Definição Português:  
Anticorpo monoclonal humanizado recombinante anti-IgE que se liga especificamente ao domínio C epsilon3 da IMUNOGLOBULINA E, o sítio de alta afinidade de ligação ao receptor de IgE. Inibe a ligação da IgE a MASTÓCITOS e a BASÓFILOS, reduzindo, assim, a gravidade da resposta alergência. É usado no controle da ASMA alérgica persistente. 
Ação Farmacológica:   Antialérgicos
Antiasmáticos
 
Qualificadores Permitidos Português:  
AD administração & dosagem AN análise
BI biossíntese CL classificação
EC economia AE efeitos adversos
RE efeitos da radiação DE efeitos dos fármacos
PO envenenamento PK farmacocinética
PD farmacologia PH fisiologia
GE genética HI história
IM imunologia IP isolamento & purificação
CF líquido cefalorraquidiano ME metabolismo
CH química BL sangue
TO toxicidade UL ultraestrutura
UR urina TU uso terapêutico
Número do Registro:   55972 
Identificador Único:   D000069444 


   COMPOSTOS QUÍMICOS E DROGAS [D]
      Aminoácidos, Peptídeos e Proteínas [D12]
         Proteínas [D12.776]
            Proteínas Sanguíneas [D12.776.124]
               Imunoproteínas [D12.776.124.486]
                  Imunoglobulinas [D12.776.124.486.485]
                     Anticorpos [D12.776.124.486.485.114]
                        Anticorpos Anti-Idiotípicos [D12.776.124.486.485.114.071]
                           Omalizumab [D12.776.124.486.485.114.071.500] 
                        Anticorpos Antiarchaea [D12.776.124.486.485.114.089]
                        Anticorpos Antibacterianos [D12.776.124.486.485.114.107] +
                        Anticorpos Biespecíficos [D12.776.124.486.485.114.125]
                        Anticorpos Bloqueadores [D12.776.124.486.485.114.143]
                        Anticorpos Catalíticos [D12.776.124.486.485.114.167]
                        Anticorpos Antifúngicos [D12.776.124.486.485.114.179]
                        Anticorpos Anti-Helmínticos [D12.776.124.486.485.114.185]
                        Anticorpos Heterófilos [D12.776.124.486.485.114.191]
                        Anticorpos Imobilizados [D12.776.124.486.485.114.207]
                        Anticorpos Monoclonais [D12.776.124.486.485.114.224] +
                        Anticorpos Antineoplásicos [D12.776.124.486.485.114.240]
                        Anticorpos Neutralizantes [D12.776.124.486.485.114.244]
                        Anticorpos Fosfo-Específicos [D12.776.124.486.485.114.248]
                        Anticorpos Antiprotozoários [D12.776.124.486.485.114.252]
                        Anticorpos Antivirais [D12.776.124.486.485.114.254] +
                        Complexo Antígeno-Anticorpo [D12.776.124.486.485.114.257]
                        Autoanticorpos [D12.776.124.486.485.114.323] +
                        Soros Imunes [D12.776.124.486.485.114.573] +
                        Alótipos de Imunoglobulina [D12.776.124.486.485.114.606] +
                        Isotipos de Imunoglobulinas [D12.776.124.486.485.114.619] +
                        Imunoglobulinas Intravenosas [D12.776.124.486.485.114.632]
                        Anticorpos Anti-Insulina [D12.776.124.486.485.114.656]
                        Isoanticorpos [D12.776.124.486.485.114.664]
                        Bandas Oligoclonais [D12.776.124.486.485.114.715]
                        Proteínas Opsonizantes [D12.776.124.486.485.114.767]
                        Planticorpos [D12.776.124.486.485.114.820]
                        Precipitinas [D12.776.124.486.485.114.837]
                        Reaginas [D12.776.124.486.485.114.890]


   COMPOSTOS QUÍMICOS E DROGAS [D]
      Aminoácidos, Peptídeos e Proteínas [D12]
         Proteínas [D12.776]
            Proteínas Sanguíneas [D12.776.124]
               Imunoproteínas [D12.776.124.486]
                  Imunoglobulinas [D12.776.124.486.485]
                     Anticorpos [D12.776.124.486.485.114]
                        Anticorpos Monoclonais [D12.776.124.486.485.114.224]
                           Anticorpos Monoclonais Humanizados [D12.776.124.486.485.114.224.060]
                              Abciximab [D12.776.124.486.485.114.224.060.125]
                              Adalimumab [D12.776.124.486.485.114.224.060.250]
                              Alemtuzumab [D12.776.124.486.485.114.224.060.313]
                              Basiliximab [D12.776.124.486.485.114.224.060.344]
                              Bevacizumab [D12.776.124.486.485.114.224.060.375]
                              Certolizumab Pegol [D12.776.124.486.485.114.224.060.500]
                              Cetuximab [D12.776.124.486.485.114.224.060.750]
                              Daclizumabe [D12.776.124.486.485.114.224.060.766]
                              Denosumab [D12.776.124.486.485.114.224.060.782]
                              Ipilimumab [D12.776.124.486.485.114.224.060.798]
                              Natalizumab [D12.776.124.486.485.114.224.060.813]
                              Nivolumabe [D12.776.124.486.485.114.224.060.829]
                              Omalizumab [D12.776.124.486.485.114.224.060.844] 
                              Palivizumab [D12.776.124.486.485.114.224.060.860]
                              Panitumumabe [D12.776.124.486.485.114.224.060.864]
                              Ranibizumab [D12.776.124.486.485.114.224.060.868]
                              Trastuzumab [D12.776.124.486.485.114.224.060.875]
                              Ustekinumab [D12.776.124.486.485.114.224.060.937]
                           Anticorpos Monoclonais Murinos [D12.776.124.486.485.114.224.075] +
                           Infliximab [D12.776.124.486.485.114.224.608]
                           Anticorpos de Cadeia Única [D12.776.124.486.485.114.224.785]


   COMPOSTOS QUÍMICOS E DROGAS [D]
      Aminoácidos, Peptídeos e Proteínas [D12]
         Proteínas [D12.776]
            Proteínas Sanguíneas [D12.776.124]
               Soroglobulinas [D12.776.124.790]
                  Imunoglobulinas [D12.776.124.790.651]
                     Anticorpos [D12.776.124.790.651.114]
                        Anticorpos Anti-Idiotípicos [D12.776.124.790.651.114.071]
                           Omalizumab [D12.776.124.790.651.114.071.500] 
                        Anticorpos Antiarchaea [D12.776.124.790.651.114.107]
                        Anticorpos Antibacterianos [D12.776.124.790.651.114.125] +
                        Anticorpos Biespecíficos [D12.776.124.790.651.114.134]
                        Anticorpos Bloqueadores [D12.776.124.790.651.114.143]
                        Anticorpos Catalíticos [D12.776.124.790.651.114.167]
                        Anticorpos Antifúngicos [D12.776.124.790.651.114.179]
                        Anticorpos Anti-Helmínticos [D12.776.124.790.651.114.185]
                        Anticorpos Heterófilos [D12.776.124.790.651.114.191]
                        Anticorpos Imobilizados [D12.776.124.790.651.114.207]
                        Anticorpos Monoclonais [D12.776.124.790.651.114.224] +
                        Anticorpos Antineoplásicos [D12.776.124.790.651.114.240]
                        Anticorpos Neutralizantes [D12.776.124.790.651.114.244]
                        Anticorpos Fosfo-Específicos [D12.776.124.790.651.114.248]
                        Anticorpos Antiprotozoários [D12.776.124.790.651.114.252]
                        Anticorpos Antivirais [D12.776.124.790.651.114.254] +
                        Complexo Antígeno-Anticorpo [D12.776.124.790.651.114.257]
                        Autoanticorpos [D12.776.124.790.651.114.323] +
                        Soros Imunes [D12.776.124.790.651.114.573] +
                        Imunoconjugados [D12.776.124.790.651.114.580] +
                        Alótipos de Imunoglobulina [D12.776.124.790.651.114.606] +
                        Isotipos de Imunoglobulinas [D12.776.124.790.651.114.619] +
                        Imunoglobulinas Intravenosas [D12.776.124.790.651.114.632]
                        Anticorpos Anti-Insulina [D12.776.124.790.651.114.656]
                        Isoanticorpos [D12.776.124.790.651.114.664]
                        Bandas Oligoclonais [D12.776.124.790.651.114.715]
                        Proteínas Opsonizantes [D12.776.124.790.651.114.767]
                        Planticorpos [D12.776.124.790.651.114.820]
                        Precipitinas [D12.776.124.790.651.114.837]
                        Reaginas [D12.776.124.790.651.114.890]


   COMPOSTOS QUÍMICOS E DROGAS [D]
      Aminoácidos, Peptídeos e Proteínas [D12]
         Proteínas [D12.776]
            Proteínas Sanguíneas [D12.776.124]
               Soroglobulinas [D12.776.124.790]
                  Imunoglobulinas [D12.776.124.790.651]
                     Anticorpos [D12.776.124.790.651.114]
                        Anticorpos Monoclonais [D12.776.124.790.651.114.224]
                           Anticorpos Monoclonais Humanizados [D12.776.124.790.651.114.224.060]
                              Abciximab [D12.776.124.790.651.114.224.060.125]
                              Adalimumab [D12.776.124.790.651.114.224.060.250]
                              Alemtuzumab [D12.776.124.790.651.114.224.060.375]
                              Basiliximab [D12.776.124.790.651.114.224.060.407]
                              Bevacizumab [D12.776.124.790.651.114.224.060.438]
                              Certolizumab Pegol [D12.776.124.790.651.114.224.060.500]
                              Cetuximab [D12.776.124.790.651.114.224.060.750]
                              Daclizumabe [D12.776.124.790.651.114.224.060.766]
                              Denosumab [D12.776.124.790.651.114.224.060.782]
                              Ipilimumab [D12.776.124.790.651.114.224.060.798]
                              Natalizumab [D12.776.124.790.651.114.224.060.813]
                              Nivolumabe [D12.776.124.790.651.114.224.060.829]
                              Omalizumab [D12.776.124.790.651.114.224.060.844] 
                              Palivizumab [D12.776.124.790.651.114.224.060.860]
                              Panitumumabe [D12.776.124.790.651.114.224.060.864]
                              Ranibizumab [D12.776.124.790.651.114.224.060.868]
                              Trastuzumab [D12.776.124.790.651.114.224.060.875]
                              Ustekinumab [D12.776.124.790.651.114.224.060.937]
                           Anticorpos Monoclonais Murinos [D12.776.124.790.651.114.224.075] +
                           Infliximab [D12.776.124.790.651.114.224.537]


   COMPOSTOS QUÍMICOS E DROGAS [D]
      Aminoácidos, Peptídeos e Proteínas [D12]
         Proteínas [D12.776]
            Globulinas [D12.776.377]
               Soroglobulinas [D12.776.377.715]
                  Imunoglobulinas [D12.776.377.715.548]
                     Anticorpos [D12.776.377.715.548.114]
                        Anticorpos Anti-Idiotípicos [D12.776.377.715.548.114.071]
                           Omalizumab [D12.776.377.715.548.114.071.500] 
                        Anticorpos Antiarchaea [D12.776.377.715.548.114.107]
                        Anticorpos Antibacterianos [D12.776.377.715.548.114.125] +
                        Anticorpos Biespecíficos [D12.776.377.715.548.114.134]
                        Anticorpos Bloqueadores [D12.776.377.715.548.114.143]
                        Anticorpos Catalíticos [D12.776.377.715.548.114.167]
                        Anticorpos Antifúngicos [D12.776.377.715.548.114.179]
                        Anticorpos Anti-Helmínticos [D12.776.377.715.548.114.185]
                        Anticorpos Heterófilos [D12.776.377.715.548.114.191]
                        Anticorpos Imobilizados [D12.776.377.715.548.114.207]
                        Anticorpos Monoclonais [D12.776.377.715.548.114.224] +
                        Anticorpos Antineoplásicos [D12.776.377.715.548.114.240]
                        Anticorpos Neutralizantes [D12.776.377.715.548.114.244]
                        Anticorpos Fosfo-Específicos [D12.776.377.715.548.114.248]
                        Anticorpos Antiprotozoários [D12.776.377.715.548.114.252]
                        Anticorpos Antivirais [D12.776.377.715.548.114.254] +
                        Complexo Antígeno-Anticorpo [D12.776.377.715.548.114.257]
                        Autoanticorpos [D12.776.377.715.548.114.323] +
                        Soros Imunes [D12.776.377.715.548.114.573] +
                        Imunoconjugados [D12.776.377.715.548.114.580] +
                        Alótipos de Imunoglobulina [D12.776.377.715.548.114.606] +
                        Isotipos de Imunoglobulinas [D12.776.377.715.548.114.619] +
                        Imunoglobulinas Intravenosas [D12.776.377.715.548.114.632]
                        Anticorpos Anti-Insulina [D12.776.377.715.548.114.656]
                        Isoanticorpos [D12.776.377.715.548.114.664]
                        Bandas Oligoclonais [D12.776.377.715.548.114.715]
                        Proteínas Opsonizantes [D12.776.377.715.548.114.767]
                        Planticorpos [D12.776.377.715.548.114.820]
                        Precipitinas [D12.776.377.715.548.114.837]
                        Reaginas [D12.776.377.715.548.114.890]


   COMPOSTOS QUÍMICOS E DROGAS [D]
      Aminoácidos, Peptídeos e Proteínas [D12]
         Proteínas [D12.776]
            Globulinas [D12.776.377]
               Soroglobulinas [D12.776.377.715]
                  Imunoglobulinas [D12.776.377.715.548]
                     Anticorpos [D12.776.377.715.548.114]
                        Anticorpos Monoclonais [D12.776.377.715.548.114.224]
                           Anticorpos Monoclonais Humanizados [D12.776.377.715.548.114.224.200]
                              Abciximab [D12.776.377.715.548.114.224.200.125]
                              Adalimumab [D12.776.377.715.548.114.224.200.250]
                              Alemtuzumab [D12.776.377.715.548.114.224.200.375]
                              Basiliximab [D12.776.377.715.548.114.224.200.407]
                              Bevacizumab [D12.776.377.715.548.114.224.200.438]
                              Certolizumab Pegol [D12.776.377.715.548.114.224.200.500]
                              Cetuximab [D12.776.377.715.548.114.224.200.750]
                              Daclizumabe [D12.776.377.715.548.114.224.200.766]
                              Denosumab [D12.776.377.715.548.114.224.200.782]
                              Ipilimumab [D12.776.377.715.548.114.224.200.798]
                              Natalizumab [D12.776.377.715.548.114.224.200.813]
                              Nivolumabe [D12.776.377.715.548.114.224.200.829]
                              Omalizumab [D12.776.377.715.548.114.224.200.844] 
                              Palivizumab [D12.776.377.715.548.114.224.200.860]
                              Panitumumabe [D12.776.377.715.548.114.224.200.864]
                              Ranibizumab [D12.776.377.715.548.114.224.200.868]
                              Trastuzumab [D12.776.377.715.548.114.224.200.875]
                              Ustekinumab [D12.776.377.715.548.114.224.200.937]
                           Anticorpos Monoclonais Murinos [D12.776.377.715.548.114.224.284] +
                           Infliximab [D12.776.377.715.548.114.224.642]