Search on: ACTIVATING TRANSCRIPTION FACTORS 
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Descriptor English:   Activating Transcription Factors 
Descriptor Spanish:   Factores de Transcripción Activadores 
Descriptor Portuguese:   Fatores Ativadores da Transcrição 
Synonyms English:   ATF Transcription Factors
Factors, ATF Transcription
Transcription Factors, ATF  
Tree Number:   D12.776.260.108.061
D12.776.930.127.061
Definition English:   Activating transcription factors were originally identified as DNA-BINDING PROTEINS that interact with early promoters from ADENOVIRUSES. They are a family of basic leucine zipper transcription factors that bind to the consensus site TGACGTCA of the cyclic AMP response element, and are closely related to CYCLIC AMP-RESPONSIVE DNA-BINDING PROTEIN. 
Indexing Annotation English:   general; prefer specifics
History Note English:   2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50953 
Unique Identifier:   D051696 

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