Search on: ANGIOTENSINOGEN 
Descriptors Found: 1
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Descriptor English:   Angiotensinogen 
Descriptor Spanish:   Angiotensinógeno 
Descriptor Portuguese:   Angiotensinogênio 
Synonyms English:   Hypertensinogen
Proangiotensin
Renin Substrate
Renin Substrate Tetradecapeptide
Renin-Substrate
Serpin A8
Tetradecapeptide, Renin Substrate  
Tree Number:   D12.644.456.073.070
D12.644.861.020
D12.776.811.070
D12.776.872.020
Definition English:   An alpha-globulin of about 453 amino acids, depending on the species. It is produced by the liver and secreted into blood circulation. Angiotensinogen is the inactive precursor of natural angiotensins. Upon successive enzyme cleavages, angiotensinogen yields angiotensin I, II, and III with amino acids numbered at 10, 8, and 7, respectively. 
Pharmacological Action:   Serine Proteinase Inhibitors
 
History Note English:   87(75); was see under ANGIOTENSINS 1975-86 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   27913 
Unique Identifier:   D000808 

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