Search on: APOLIPOPROTEIN A-I 
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Descriptor English:   Apolipoprotein A-I 
Descriptor Spanish:   Apolipoproteína A-I 
Descriptor Portuguese:   Apolipoproteína A-I 
Synonyms English:   Apo A I Isoproteins
Apo A-1
Apo A-I
Apo A-I Isoproteins
Apo A1
Apo AI
ApoA-1
ApoA-I
Apolipoprotein A 1
Apolipoprotein A I
Apolipoprotein A I Isoprotein 2
Apolipoprotein A I Isoprotein 4
Apolipoprotein A I Isoproteins
Apolipoprotein A-1
Apolipoprotein A-I Isoprotein-2
Apolipoprotein A-I Isoprotein-4
Apolipoprotein A-I Isoproteins
Apolipoprotein A1
Apolipoprotein AI
Apolipoprotein AI Propeptide
Pro Apo A I
Pro Apolipoprotein A I
Pro-Apo A-I
Pro-Apolipoprotein A-I
Proapolipoprotein AI  
Tree Number:   D10.532.091.200.100
D12.776.070.400.200.100
D12.776.521.120.200.100
Definition English:   The most abundant protein component of HIGH DENSITY LIPOPROTEINS or HDL. This protein serves as an acceptor for CHOLESTEROL released from cells thus promoting efflux of cholesterol to HDL then to the LIVER for excretion from the body (reverse cholesterol transport). It also acts as a cofactor for LECITHIN CHOLESTEROL ACYLTRANSFERASE that forms CHOLESTEROL ESTERS on the HDL particles. Mutations of this gene APOA1 cause HDL deficiency, such as in FAMILIAL ALPHA LIPOPROTEIN DEFICIENCY DISEASE and in some patients with TANGIER DISEASE. 
History Note English:   1992 (1974); for PRO-APOLIPOPROTEIN A-I (NM) use APOLIPOPROTEINS A & PROTEIN PRECURSORS 1983-2006; for APOLIPOPROTEIN A-I ISOPROTEINS (NM) use APOLIPOPROTEINS A 1980-2006 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30252 
Unique Identifier:   D016632 

Occurrence in VHL:
 
LILACS    
MEDLINE    
IBECS    

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