Search on: CARCINOID HEART DISEASE 
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Descriptor English:   Carcinoid Heart Disease 
Descriptor Spanish:   Cardiopatía Carcinoide 
Descriptor Portuguese:   Doença Cardíaca Carcinoide 
Synonyms English:   Carcinoid Heart Diseases
Heart Disease, Carcinoid
Heart Diseases, Carcinoid  
Tree Number:   C04.557.465.625.650.200.500.205
C04.557.470.200.025.200.500.205
C04.557.580.625.650.200.500.205
C14.280.104
Definition English:   Cardiac manifestation of gastrointestinal CARCINOID TUMOR that metastasizes to the liver. Substances secreted by the tumor cells, including SEROTONIN, promote fibrous plaque formation in ENDOCARDIUM and its underlying layers. These deposits cause distortion of the TRICUSPID VALVE and the PULMONARY VALVE eventually leading to STENOSIS and valve regurgitation. 
History Note English:   91(75)(64-72); was see under MALIGNANT CARCINOID SYNDROME 1964-90 (Prov 1964-72) 
Allowable Qualifiers English:  
BL blood CF cerebrospinal fluid
CI chemically induced CL classification
CO complications CN congenital
DI diagnosis DG diagnostic imaging
DH diet therapy DT drug therapy
EC economics EM embryology
EN enzymology EP epidemiology
EH ethnology ET etiology
GE genetics HI history
IM immunology ME metabolism
MI microbiology MO mortality
NU nursing PS parasitology
PA pathology PP physiopathology
PC prevention & control PX psychology
RT radiotherapy RH rehabilitation
SU surgery TH therapy
UR urine VE veterinary
VI virology  
Record Number:   2318 
Unique Identifier:   D002275 

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