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Descriptor English: Cardenolides
Descriptor Spanish: Cardenólidos
Descriptor cardenólidos
Entry term(s) cardenólido
Scope note: Esteroides C(23) con grupos metilo en C-10 y C-13 y una lactona de cinco miembros en C-17. Son agliconas que componen los GLICÓSIDOS CARDÍACOS y deben tener como mínimo un doble enlace en la molécula. Esta clase incluye los cardadienólidos y cardatrienólidos. Entre los miembros de esta clase se encuentran la DIGITOXINA y la DIGOXINA, así como sus derivados y las ESTROFANTINAS.
Descriptor Portuguese: Cardenolídeos
Descriptor French: Cardénolides
Entry term(s): Cardenolide
Tree number(s): D04.210.500.155.580.130
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002298
Scope note: C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
Annotation: includes cardadienolides & cardatrienolides; do not confuse with CARDANOLIDES
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Previous Indexing: Cardanolides (1968-1976)
Public MeSH Note: 77
History Note: 77
DeCS ID: 2342
Unique ID: D002298
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1977/01/01
Date of Entry: 1976/04/16
Revision Date: 2020/05/27
Cardenolides - Preferred
Concept UI M0003448
Scope note C(23)-steroids with methyl groups at C-10 and C-13 and a five-membered lactone at C-17. They are aglycone constituents of CARDIAC GLYCOSIDES and must have at least one double bond in the molecule. The class includes cardadienolides and cardatrienolides. Members include DIGITOXIN and DIGOXIN and their derivatives and the STROPHANTHINS.
Preferred term Cardenolides
Entry term(s) Cardenolide



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