Search on: CEREBROSIDE-SULFATASE 
Descriptors Found: 1
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Descriptor English:   Cerebroside-Sulfatase 
Descriptor Spanish:   Cerebrósido Sulfatasa 
Descriptor Portuguese:   Cerebrosídeo Sulfatase 
Synonyms English:   Arylsulfatase A
Cerebroside Sulfatase
Sulfatase, Sulfatidate
Sulfatidate Sulfatase  
Tree Number:   D08.811.277.352.827.070.250
Definition English:   An enzyme that catalyzes the hydrolysis of cerebroside 3-sulfate (sulfatide) to yield a cerebroside and inorganic sulfate. A marked deficiency of arylsulfatase A, which is considered the heat-labile component of cerebroside sulfatase, has been demonstrated in all forms of metachromatic leukodystrophy (LEUKODYSTROPHY, METACHROMATIC). EC 3.1.6.8. 
Indexing Annotation English:   /defic: consider also LEUKODYSTROPHY, METACHROMATIC
See Related English:   Leukodystrophy, Metachromatic
 
History Note English:   87(76); was see under SULFATASES 1976-86 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   2592 
Unique Identifier:   D002553 

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