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Descriptor English: Dihydroxyphenylalanine
Descriptor Spanish: Dihidroxifenilalanina
Descriptor dihidroxifenilalanina
Entry term(s) dopa
Scope note: Derivado betahidroxilado de la fenilalanina. La forma D de la hidroxifenilalanina tiene menos actividad fisiológica que la forma L y se utiliza frecuentemente en experimentación para determinar si los efectos farmacológicos de la LEVODOPA son estereoespecíficos.
Descriptor Portuguese: Di-Hidroxifenilalanina
Descriptor French: Dopa
Entry term(s): 3 Hydroxy DL tyrosine
3,4 Dihydroxyphenylalanine
3,4-Dihydroxyphenylalanine
3-Hydroxy-DL-tyrosine
Dihydroxyphenylalanine Hydrochloride, (2:1)
Dopa
beta Hydroxytyrosine
beta-Hydroxytyrosine
Tree number(s): D02.092.311.200
D02.455.426.559.389.657.166.175.200
D12.125.072.050.685.400
D12.125.072.050.875.130
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004295
Scope note: A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
Annotation: check text to see if LEVODOPA; (L-DOPA); is not meant instead
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Dopamine Agents
Registry Number: 63-84-3
CAS Type 1 Name: DL-Tyrosine, 3-hydroxy-
Public MeSH Note: 2002; see DOPA 1966-2001
History Note: 2002(1966); for BETA-HYDROXYTYROSINE use DIHYDOXYPHENYLALANINE (NM) 1989-1991
Related: Dopa Decarboxylase MeSH
Dopamine MeSH
DeCS ID: 23986
Unique ID: D004295
NLM Classification: WK 725
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2002/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/06/30
Dihydroxyphenylalanine - Preferred
Concept UI M0006754
Scope note A beta-hydroxylated derivative of phenylalanine. The D-form of dihydroxyphenylalanine has less physiologic activity than the L-form and is commonly used experimentally to determine whether the pharmacological effects of LEVODOPA are stereospecific.
Preferred term Dihydroxyphenylalanine
Entry term(s) 3 Hydroxy DL tyrosine
3,4 Dihydroxyphenylalanine
3,4-Dihydroxyphenylalanine
3-Hydroxy-DL-tyrosine
Dopa
beta Hydroxytyrosine
beta-Hydroxytyrosine
Dihydroxyphenylalanine Hydrochloride, (2:1) - Narrower
Concept UI M0330404
Preferred term Dihydroxyphenylalanine Hydrochloride, (2:1)



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