Search on: FIBRINOLYSIN 
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Descriptor English:   Fibrinolysin 
Descriptor Spanish:   Fibrinolisina 
Descriptor Portuguese:   Fibrinolisina 
Synonyms English:   Fibrogammin
Glu Plasmin
Glu-Plasmin
Plasmin
Protease F
Thrombolysin  
Tree Number:   D08.811.277.656.300.760.330
D08.811.277.656.959.350.330
Definition English:   A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins. 
Pharmacological Action:   Fibrinolytic Agents
 
History Note English:   2010, 1963-1992; 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   30897 
Unique Identifier:   D005341 

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