Search on: GRANULOCYTE COLONY-STIMULATING FACTOR 
Descriptors Found: 1
Displaying: 1 .. 1  

 1 / 1 DeCS     
Descriptor English:   Granulocyte Colony-Stimulating Factor 
Descriptor Spanish:   Factor Estimulante de Colonias de Granulocitos 
Descriptor Portuguese:   Fator Estimulador de Colônias de Granulócitos 
Synonyms English:   G-CSF  
Tree Number:   D12.644.276.374.410.240.350
D12.776.395.240.200
D12.776.467.374.410.240.350
D23.529.374.410.240.350
Definition English:   A glycoprotein of MW 25 kDa containing internal disulfide bonds. It induces the survival, proliferation, and differentiation of neutrophilic granulocyte precursor cells and functionally activates mature blood neutrophils. Among the family of colony-stimulating factors, G-CSF is the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. 
See Related English:   Receptors, Granulocyte Colony-Stimulating Factor
 
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   28968 
Unique Identifier:   D016179 

Occurrence in VHL:
 
LILACS    
MEDLINE    
BDENF    
IBECS    

Similar:

 
DeCS