Search on: LYSOSOMES 
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Descriptor English:   Lysosomes 
Descriptor Spanish:   Lisosomas 
Descriptor Portuguese:   Lisossomos 
Synonyms English:   Lysosome  
Tree Number:   A11.284.430.214.190.875.190.550
Definition English:   A class of morphologically heterogeneous cytoplasmic particles in animal and plant tissues characterized by their content of hydrolytic enzymes and the structure-linked latency of these enzymes. The intracellular functions of lysosomes depend on their lytic potential. The single unit membrane of the lysosome acts as a barrier between the enzymes enclosed in the lysosome and the external substrate. The activity of the enzymes contained in lysosomes is limited or nil unless the vesicle in which they are enclosed is ruptured. Such rupture is supposed to be under metabolic (hormonal) control. (From Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed) 
History Note English:   65(64) 
Allowable Qualifiers English:  
CH chemistry CL classification
DE drug effects EN enzymology
GE genetics IM immunology
ME metabolism MI microbiology
PS parasitology PA pathology
PH physiology RE radiation effects
TR transplantation UL ultrastructure
VI virology  
Record Number:   8419 
Unique Identifier:   D008247 

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