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Descriptor English:   Mixed Function Oxygenases 
Descriptor Spanish:   Oxigenasas de Función Mixta 
Descriptor Portuguese:   Oxigenases de Função Mista 
Synonyms English:   Hydroxylases
Mixed Function Oxidases
Oxidases, Mixed Function
Oxygenases, Mixed Function  
Tree Number:   D08.811.682.690.708
Definition English:   Widely distributed enzymes that carry out oxidation-reduction reactions in which one atom of the oxygen molecule is incorporated into the organic substrate; the other oxygen atom is reduced and combined with hydrogen ions to form water. They are also known as monooxygenases or hydroxylases. These reactions require two substrates as reductants for each of the two oxygen atoms. There are different classes of monooxygenases depending on the type of hydrogen-providing cosubstrate (COENZYMES) required in the mixed-function oxidation. 
Indexing Annotation English:   do not confuse with HYDRO-LYASES
History Note English:   2003 (1966) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   7067 
Unique Identifier:   D006899 

Occurrence in VHL: