DeCS

Descriptor English:

Myosins

Descriptor Spanish:

Miosinas

Spanish from Spain

Descriptor	miosinas
Entry term(s)	ATPasa de miosina
Scope note:	Superfamilia diversa de proteínas que actúan como proteínas de traslado. Comparten características comunes de capacidad de unión a las ACTINAS y de hidrólisis de MgATP. Las miosinas están formadas en general por cadenas pesadas que intervienen en la locomoción y cadenas ligeras que actúan en la regulación. En la estructura de la cadena pesada de la miosina existen tres dominios: la cabeza, el cuello y la cola. La región de la cabeza de la cadena pesada contiene el dominio de unión a la actina y el dominio MgATPasa, que proporciona energía para la locomoción; la región del cuello interviene en la unión de las cadenas ligeras; y la región de la cola proporciona un punto de anclaje que mantiene la posición de la cadena pesada. La superfamilia de las miosinas se organiza en clases estructurales conforme al tipo de las subunidades que contienen y a su disposición.

Descriptor Portuguese:

Miosinas

Descriptor French:

Myosines

Entry term(s):

ATPase, Actin Activated
ATPase, Actin-Activated
ATPase, Actomyosin
ATPase, Myosin
Actin Activated ATPase
Actin-Activated ATPase
Actomyosin ATPase
Actomyosin Adenosinetriphosphatase
Adenosine Triphosphatase, Myosin
Adenosinetriphosphatase, Actomyosin
Adenosinetriphosphatase, Myosin
Myosin
Myosin ATPase
Myosin Adenosine Triphosphatase
Myosin Adenosinetriphosphatase

Tree number(s):

D05.750.078.730.475
D08.811.277.040.025.193.750
D12.776.210.500.600
D12.776.220.525.475

RDF Unique Identifier:

https://id.nlm.nih.gov/mesh/D009218

Scope note:

A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.

Annotation:

general or unspecified; prefer specifics

Allowable Qualifiers:

AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine

Registry Number:

EC 3.6.4.1

Previous Indexing:

Adenosine Triphosphatase (1966-1968)
Muscle Proteins (1966-1970)

Public MeSH Note:

2002; see MYOSIN 1973-2001, see MUSCLE PROTEINS 1969-1972; see ADENOSINE TRIPHOSPHATASE 1963-1968; for MYOSIN ATPASE see MYOSIN ATPASE 1993-2001, see ADENOSINE TRIPHOSPHATASE, MYOSIN 1989-1992, see ADENOSINE TRIPHOSPHATASE 1984-1988; for ADENOSINE TRIPHOSPHATASE, MYOSIN & MYOSIN ADENOSINETRIPHOSPHATASE see MYOSIN ATPASE 1993-2001; for ACTOMYOSIN ADENOSINETRIPHOSPHATASE & ADENOSINETRIPHOSPHATASE, ACTOMYOSIN see MYOSIN ATPASE 1993-2001, see ADENOSINE TRIPHOSPHATASE, MYOSIN 1989-92; for ACTOMYOSIN ATPASE see MYOSIN ATPASE 1993-2001, see ADENOSINE TRIPHOSPHATASE, MYOSIN 1989-1992, see ADENOSINE TRIPHOSPHATASE 1985-1988

History Note:

2002(1971); use ADENOSINE TRIPHOSPHATASE 1963-1968; for MYOSIN ATPASE use ADENOSINETRIPHOSPHATASE 1984-1988; for ACTOMYOSIN ATPASE use ADENOSINETRIPHOSPHATASE 1985-1988

Concept UI	M0014361
Scope note	A diverse superfamily of proteins that function as translocating proteins. They share the common characteristics of being able to bind ACTINS and hydrolyze MgATP. Myosins generally consist of heavy chains which are involved in locomotion, and light chains which are involved in regulation. Within the structure of myosin heavy chain are three domains: the head, the neck and the tail. The head region of the heavy chain contains the actin binding domain and MgATPase domain which provides energy for locomotion. The neck region is involved in binding the light-chains. The tail region provides the anchoring point that maintains the position of the heavy chain. The superfamily of myosins is organized into structural classes based upon the type and arrangement of the subunits they contain.
Preferred term	Myosins
Entry term(s)	ATPase, Actin Activated ATPase, Actin-Activated ATPase, Myosin Actin Activated ATPase Actin-Activated ATPase Adenosine Triphosphatase, Myosin Adenosinetriphosphatase, Myosin Myosin Myosin ATPase Myosin Adenosine Triphosphatase Myosin Adenosinetriphosphatase

Concept UI	M0375356
Preferred term	Actomyosin Adenosinetriphosphatase
Entry term(s)	ATPase, Actomyosin Actomyosin ATPase Adenosinetriphosphatase, Actomyosin

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