Search on: NEUROMUSCULAR DEPOLARIZING AGENTS 
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Descriptor English:   Neuromuscular Depolarizing Agents 
Descriptor Spanish:   Fármacos Neuromusculares Despolarizantes 
Descriptor Portuguese:   Fármacos Neuromusculares Despolarizantes 
Synonyms English:   Agents, Neuromuscular Depolarizing
Blockers, Depolarizing
Depolarizing Agents, Neuromuscular
Depolarizing Blockers
Depolarizing Muscle Relaxants
Muscle Relaxants, Depolarizing
Relaxants, Depolarizing Muscle  
Tree Number:   D27.505.696.663.700.710.550
Definition English:   Drugs that interrupt transmission at the skeletal neuromuscular junction by causing sustained depolarization of the motor end plate. These agents are primarily used as adjuvants in surgical anesthesia to cause skeletal muscle relaxation. 
History Note English:   70; LEPTOCURARES was see NEUROMUSCULAR DEPOLARIZING AGENTS 1970-92; MUSCLE RELAXANTS was see under CURARE-LIKE AGENTS & MUSCLE RELAXANTS, CENTRAL & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74, was heading 1963-69 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   9659 
Unique Identifier:   D009467 

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