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Descriptor English: Sparteine
Descriptor Spanish: Esparteína
Descriptor esparteína
Entry term(s) (7S-(7-alfa,7a-alfa,14-alfa,14a-beta))-dodecahidro-7,14-metano-2H,6H-dipirido(1,2-a:1',2'-e)(1,5)diazocina
lupinidina
paquicarpina
Scope note: Alcaloide de la quinolizidina aislado de varios FABACEAE, incluído LUPINUS, SPARTIUM y CYTISUS. Se ha utilizado como agente oxitócico y antiarrítmico. también ha servido como indicador del genotipo CYP2D6.
Descriptor Portuguese: Esparteína
Descriptor French: Spartéine
Entry term(s): 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-
Anhydrous, Sparteine Sulfate
D-sparteine
Depasan Retard
Genisteine Alkaloid
L-Sparteine
Lupinidin
Lupinidine
Pachycarpine
Pachycarpine Sulfate (1:1), Pentahydrate, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Hydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Hydrochloride, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Monohydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Monohydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Sulfate
Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer
Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Sulfate Anhydrous
Sparteine, (+)-Isomer
Sparteine, (-)-Isomer
Sparteine, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine, (7R-(7alpha,7abeta,14alpha,14abeta))-Isomer
Sparteine, (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer
Sparteine, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine, (7S-(7alpha,7abeta,14alpha,14abeta))-Isomer
Sulfate Anhydrous, Sparteine
alpha Isosparteine
alpha-Isosparteine
beta Isosparteine
beta-Isosparteine
Tree number(s): D03.132.722.750
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D013034
Scope note: A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anti-Arrhythmia Agents
Oxytocics
Registry Number: 298897D62S
CAS Type 1 Name: 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-
Public MeSH Note: 1963; PACHYCARPINE was indexed under SPARTEINE 1973-2001
History Note: 1963; for PACHYCARPINE use SPARTEINE(NM) 1973-2001
DeCS ID: 13415
Unique ID: D013034
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1963/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Sparteine - Preferred
Concept UI M0020199
Scope note A quinolizidine alkaloid isolated from several FABACEAE including LUPINUS; SPARTIUM; and CYTISUS. It has been used as an oxytocic and an anti-arrhythmia agent. It has also been of interest as an indicator of CYP2D6 genotype.
Preferred term Sparteine
Entry term(s) 7,14-Methano-2H,6H-dipyrido(1,2-a:1',2'-e)(1,5)diazocine, dodecahydro-, (7S-(7alpha,7aalpha,14alpha,14abeta))-
L-Sparteine
Lupinidin
Lupinidine
Sparteine, (-)-Isomer
Sparteine, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Hydrochloride, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer - Narrower
Concept UI M0308499
Preferred term Sparteine Hydrochloride, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer - Narrower
Concept UI M0308490
Preferred term Sparteine Hydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Monohydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer - Narrower
Concept UI M0308492
Preferred term Sparteine Monohydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Monohydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer - Narrower
Concept UI M0308496
Preferred term Sparteine Monohydroiodide, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Sulfate - Narrower
Concept UI M0308498
Preferred term Sparteine Sulfate
Entry term(s) Pachycarpine Sulfate (1:1), Pentahydrate, (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer - Narrower
Concept UI M0308497
Preferred term Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer
Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer - Narrower
Concept UI M0308491
Preferred term Sparteine Sulfate (1:1), (7S-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Sparteine, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer - Related but not broader or narrower
Concept UI M0045265
Preferred term Sparteine, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer
Entry term(s) D-sparteine
Pachycarpine
Sparteine, (+)-Isomer
Sparteine, (7R-(7alpha,7abeta,14alpha,14abeta))-Isomer - Narrower
Concept UI M0308495
Preferred term Sparteine, (7R-(7alpha,7abeta,14alpha,14abeta))-Isomer
Sparteine, (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer - Related but not broader or narrower
Concept UI M0020201
Preferred term Sparteine, (7S-(7alpha,7aalpha,14alpha,14aalpha))-Isomer
Entry term(s) Genisteine Alkaloid
alpha Isosparteine
alpha-Isosparteine
Sparteine, (7S-(7alpha,7abeta,14alpha,14abeta))-Isomer - Related but not broader or narrower
Concept UI M0020202
Preferred term Sparteine, (7S-(7alpha,7abeta,14alpha,14abeta))-Isomer
Entry term(s) beta Isosparteine
beta-Isosparteine
Sparteine Sulfate Anhydrous - Narrower
Concept UI M0582618
Preferred term Sparteine Sulfate Anhydrous
Entry term(s) Anhydrous, Sparteine Sulfate
Sulfate Anhydrous, Sparteine
Depasan Retard - Narrower
Concept UI M0020198
Preferred term Depasan Retard
Sparteine Hydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer - Narrower
Concept UI M0308493
Preferred term Sparteine Hydrochloride, (7R-(7alpha,7aalpha,14alpha,14abeta))-Isomer



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