Search on: THYROXINE 
Descriptors Found: 1
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Descriptor English:   Thyroxine 
Descriptor Spanish:   Tiroxina 
Descriptor Portuguese:   Tiroxina 
Synonyms English:   3,5,3',5'-Tetraiodothyronine
Berlthyrox
Dexnon
Eferox
Eltroxin
Eltroxine
Euthyrox
Eutirox
L Thyrox
L Thyroxin Henning
L Thyroxin beta
L Thyroxine
L Thyroxine Roche
L-3,5,3',5'-Tetraiodothyronine
L-Thyrox
L-Thyroxin Henning
L-Thyroxin beta
L-Thyroxine
L-Thyroxine Roche
Levo T
Levo-T
Levothroid
Levothyroid
Levothyroxin Deladande
Levothyroxin Delalande
Levothyroxine
Levothyroxine Sodium
Levoxine
Levoxyl
Lévothyrox
Novothyral
Novothyrox
O-(4-Hydroxy-3,5-diiodophenyl) 3,5-diiodo-L-tyrosine
O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine
Oroxine
Sodium Levothyroxine
Synthroid
Synthrox
T4 Thyroid Hormone
Thevier
Thyrax
Thyroid Hormone, T4
Thyroxin
Tiroidine
Tiroxina Leo
Unithroid  
Tree Number:   D06.472.931.812
D12.125.072.050.767
Definition English:   The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. 
Indexing Annotation English:   /blood: consider also HYPERTHYROXINEMIA
See Related English:   Hyperthyroxinemia
Receptors, Thyroid Hormone
 
History Note English:   1965; use THYROXIN 1963-1964; for LEVOTHYROXINE use LEVOTHYROXINE 1991-2001, use THYROXINE 1966-1990 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   14360 
Unique Identifier:   D013974 

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