Search on: TRANSFORMING GROWTH FACTORS 
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Descriptor English:   Transforming Growth Factors 
Descriptor Spanish:   Factores de Crecimiento Transformadores 
Descriptor Portuguese:   Fatores de Crescimento Transformadores 
Synonyms English:   Factor, Transforming Growth
Factors, Transforming Growth
Growth Factor, Transforming
Growth Factors, Transforming
Transforming Growth Factor  
Tree Number:   D12.644.276.963
D12.776.467.960
D23.529.960
Definition English:   Hormonally active polypeptides that can induce the transformed phenotype when added to normal, non-transformed cells. They have been found in culture fluids from retrovirally transformed cells and in tumor-derived cells as well as in non-neoplastic sources. Their transforming activities are due to the simultaneous action of two otherwise unrelated factors, TRANSFORMING GROWTH FACTOR ALPHA and TRANSFORMING GROWTH FACTOR BETA. 
Indexing Annotation English:   general or unspecified; prefer specifics
History Note English:   89 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   23851 
Unique Identifier:   D015291 

Occurrence in VHL:
 
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