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Descriptor English: Nalorphine
Descriptor Spanish: Nalorfina
Descriptor nalorfina
Entry term(s) alilnormofina
Scope note: Antagonista narcótico con algunas propiedades agonistas. Es antagonista de los receptores opioides mu y agonista de los receptores opioides kappa. Administrada sola produce un amplio espectro de efectos desagradables y se considera clínicamente obsoleta.
Descriptor Portuguese: Nalorfina
Descriptor French: Nalorphine
Entry term(s): Allylnormorphine
Hydrobromide, Nalorphine
Hydrochloride, Nalorphine
Lethidrone
Nalorphine Hydrobromide
Nalorphine Hydrochloride
Nalorphine, (14 alpha)-Isomer
Nalorphine, L-tartrate (1:1)
Tree number(s): D03.132.577.249.656
D03.605.497.694
D03.633.400.686.694
D04.615.723.795.656
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D009269
Scope note: A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Narcotic Antagonists
Registry Number: U59WB2WRY2
CAS Type 1 Name: Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-(2-propenyl)-, (5alpha,6alpha)-
DeCS ID: 9461
Unique ID: D009269
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/05/31
Nalorphine - Preferred
Concept UI M0014439
Scope note A narcotic antagonist with some agonist properties. It is an antagonist at mu opioid receptors and an agonist at kappa opioid receptors. Given alone it produces a broad spectrum of unpleasant effects and it is considered to be clinically obsolete.
Preferred term Nalorphine
Entry term(s) Allylnormorphine
Nalorphine Hydrochloride - Narrower
Concept UI M0330061
Preferred term Nalorphine Hydrochloride
Entry term(s) Hydrochloride, Nalorphine
Nalorphine, L-tartrate (1:1) - Narrower
Concept UI M0330062
Preferred term Nalorphine, L-tartrate (1:1)
Lethidrone - Narrower
Concept UI M0014440
Preferred term Lethidrone
Nalorphine, (14 alpha)-Isomer - Related but not broader or narrower
Concept UI M0330060
Preferred term Nalorphine, (14 alpha)-Isomer
Nalorphine Hydrobromide - Narrower
Concept UI M0330059
Preferred term Nalorphine Hydrobromide
Entry term(s) Hydrobromide, Nalorphine



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