Search on: ACID SENSING ION CHANNELS 
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Descriptor English:   Acid Sensing Ion Channels 
Descriptor Spanish:   Canales Iónicos Sensibles al Ácido 
Descriptor Portuguese:   Canais Iônicos Sensíveis a Ácido 
Synonyms English:   ASIC Channel
Acid-Sensing Ion Channels
Proton Gated Sodium Channels
Proton-Gated Sodium Channels
Sodium Channels, Proton-Gated  
Tree Number:   D12.776.157.530.400.875.050
D12.776.543.550.450.875.050
D12.776.543.585.400.875.050
D12.776.631.024
Definition English:   A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions. 
Entry Combination - descr/qualif English:   Acid Sensing Ion Channels/antagonists & inhibitors use Acid Sensing Ion Channel Blockers
Acid Sensing Ion Channels/agonists use Sodium Channel Agonists
 
History Note English:   2013 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54944 
Unique Identifier:   D062565 

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