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Descriptor English: Amifostine
Descriptor Spanish: Amifostina
Descriptor amifostina
Entry term(s) acido aminopropilaminoetiltiofosfórico
amifostina anhidra
amifostina mono-hidratado
amifostina trihidratada
aminopropilaminoetiltiofosfato
ethio
ethiofos
gammaphos
Scope note: Fosforotiato propuesto como agente protector frente a las radiaciones. Causa vasodilatación esplénica y puede bloquear los ganglios autonómicos.
Descriptor Portuguese: Amifostina
Descriptor French: Amifostine
Entry term(s): APAETP
Amifostine Anhydrous
Amifostine Disodium Salt
Amifostine Monohydrate
Amifostine Monohydrochloride
Amifostine Trihydrate
Aminopropyl Aminoethylthiophosphate
Aminopropylaminoethylthiophosphate
Aminopropylaminoethylthiophosphoric Acid
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
Ethiofos
Ethiofos Anhydrous
Ethyol
Gammaphos
NSC 296961
NSC-296961
NSC296961
S-(N-(3-Aminopropyl)-2-aminoethyl)thiophosphoric Acid
WR 2721
WR-2721
WR2721
YM 08310
YM-08310
YM08310
Tree number(s): D02.705.400.625.050
D02.705.539.345.050
D02.886.300.692.050
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D004999
Scope note: A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AN analysis
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
Pharm Action: Radiation-Protective Agents
Registry Number: M487QF2F4V
CAS Type 1 Name: Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester)
Previous Indexing: Diamines (1974-1976)
Organothiophosphorus Compounds (1972-1976)
Public MeSH Note: 1994; was ETHIOFOS 1985-1993 (see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1985-1990); was WR 2721 see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1977-1984
Online Note: use AMIFOSTINE to search ETHIOFOS 1985-93 & WR 2721 1977-84
History Note: 1994; was ETHIOFOS 1985-1993 (see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1985-1990); was WR 2721 see under ORGANOTHIOPHOSPHORUS COMPOUNDS 1977-1984
DeCS ID: 31835
Unique ID: D004999
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1976/04/13
Revision Date: 2018/05/30
Amifostine - Preferred
Concept UI M0007867
Scope note A phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Preferred term Amifostine
Entry term(s) APAETP
Aminopropylaminoethylthiophosphoric Acid - Broader
Concept UI M000623464
Preferred term Aminopropylaminoethylthiophosphoric Acid
Entry term(s) S-(N-(3-Aminopropyl)-2-aminoethyl)thiophosphoric Acid
Gammaphos - Narrower
Concept UI M000623468
Preferred term Gammaphos
Ethiofos - Narrower
Concept UI M000623467
Preferred term Ethiofos
Amifostine Disodium Salt - Narrower
Concept UI M0330364
Preferred term Amifostine Disodium Salt
Amifostine Monohydrate - Narrower
Concept UI M0330365
Preferred term Amifostine Monohydrate
Amifostine Trihydrate - Narrower
Concept UI M000638457
Preferred term Amifostine Trihydrate
Aminopropylaminoethylthiophosphate - Narrower
Concept UI M0007868
Preferred term Aminopropylaminoethylthiophosphate
Entry term(s) Aminopropyl Aminoethylthiophosphate
Ethyol - Narrower
Concept UI M0432472
Preferred term Ethyol
NSC-296961 - Narrower
Concept UI M0352164
Preferred term NSC-296961
Entry term(s) NSC 296961
NSC296961
Amifostine Anhydrous - Narrower
Concept UI M0585621
Preferred term Amifostine Anhydrous
Entry term(s) Ethiofos Anhydrous
WR-2721 - Narrower
Concept UI M0352163
Preferred term WR-2721
Entry term(s) WR 2721
WR2721
YM-08310 - Narrower
Concept UI M0352162
Preferred term YM-08310
Entry term(s) YM 08310
YM08310
Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate - Narrower
Concept UI M000642421
Preferred term Ethanethiol, 2-((3-aminopropyl)amino)-, dihydrogen phosphate (ester), trihydrate
Amifostine Monohydrochloride - Narrower
Concept UI M0330363
Preferred term Amifostine Monohydrochloride



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