Search on: AMYLOID PRECURSOR PROTEIN SECRETASES 
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Descriptor English:   Amyloid Precursor Protein Secretases 
Descriptor Spanish:   Secretasas de la Proteína Precursora del Amiloide 
Descriptor Portuguese:   Secretases da Proteína Precursora do Amiloide 
Synonyms English:   APP Secretase
Amyloid Precursor Protein Secretase
Secretase
Secretase, APP
Secretases
alpha Secretase
alpha-Secretase
beta Secretase
beta-Secretase
gamma Secretase
gamma-Secretase  
Tree Number:   D08.811.277.656.300.032
Definition English:   Endopeptidases that are specific for AMYLOID PROTEIN PRECURSOR. Three secretase subtypes referred to as alpha, beta, and gamma have been identified based upon the region of amyloid protein precursor they cleave. 
History Note English:   2007(1992) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52219 
Unique Identifier:   D053829 

Occurrence in VHL:
 
LILACS    
MEDLINE    
IBECS    

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