Search on: ANOCTAMIN-1 
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Descriptor English:   Anoctamin-1 
Descriptor Spanish:   Anoctamina-1 
Descriptor Portuguese:   Anoctamina-1 
Synonyms English:   Anoctamin 1
TMEM16A Protein
Transmembrane Protein 16A  
Tree Number:   D12.776.157.530.400.175.032.500
Definition English:   An anoctamin chloride channel expressed at high levels in the liver, skeletal muscle, and gastrointestinal muscles that functions in transepithelial anion transport and smooth muscle contraction. It is essential for the function of the INTERSTITIAL CELLS OF CAJAL and plays a major role in chloride conduction by airway epithelial cells and in tracheal cartilage development. 
History Note English:   2018 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   57080 
Unique Identifier:   D000075369 

Occurrence in VHL: