| Descriptor English: | Anoctamins | ||||||
| Descriptor Spanish: |
Anoctaminas
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| Descriptor Portuguese: | Anoctaminas | ||||||
| Descriptor French: | Anoctamines | ||||||
| Entry term(s): |
Anoctamin Protein Family, TMEM16 TMEM16 Protein Family TMEM16 Proteins |
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| Tree number(s): |
D12.776.157.530.400.175.032 D12.776.543.550.450.175.032 D12.776.543.585.400.175.032 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D000075368 | ||||||
| Scope note: | A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding. |
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| Allowable Qualifiers: |
AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BI biosynthesis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis DE drug effects DF deficiency EC economics GE genetics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PH physiology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UL ultrastructure UR urine |
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| Previous Indexing: |
Chloride Channels (2009-2017) |
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| Public MeSH Note: | 2018 |
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| History Note: | 2018 |
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| DeCS ID: | 57079 | ||||||
| Unique ID: | D000075368 | ||||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||||
| Date Established: | 2018/01/01 | ||||||
| Date of Entry: | 2017/07/11 | ||||||
| Revision Date: | 2017/05/24 |
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CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins -
CHEMICALS AND DRUGS
Amino Acids, Peptides, and Proteins [D12]Amino Acids, Peptides, and Proteins
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Anoctamins
- Preferred
| Concept UI |
M000630244 |
| Scope note | A family of transmembrane proteins that function primarily as calcium-activated chloride channels. Structurally, they form a homodimer where each subunit consists of eight transmembrane helices with the N and C terminals exposed to the cytosol. The regions between helices 5 and 7 may be important for ion pore formation and calcium ion binding. |
| Preferred term | Anoctamins |
| Entry term(s) |
Anoctamin Protein Family, TMEM16 TMEM16 Protein Family TMEM16 Proteins |
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