Search on: ANTIBODIES, MONOCLONAL, HUMANIZED 
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Descriptor English:   Antibodies, Monoclonal, Humanized 
Descriptor Spanish:   Anticuerpos Monoclonales Humanizados 
Descriptor Portuguese:   Anticorpos Monoclonais Humanizados 
Synonyms English:   Antibodies, Humanized
Humanized Antibodies  
Tree Number:   D12.776.124.486.485.114.224.060
D12.776.124.790.651.114.224.060
D12.776.377.715.548.114.224.200
Definition English:   Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab. 
History Note English:   2012 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54578 
Unique Identifier:   D061067 

Occurrence in VHL:
 
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