Search on: ANTIBODY-DEPENDENT CELL CYTOTOXICITY 
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Descriptor English:   Antibody-Dependent Cell Cytotoxicity 
Descriptor Spanish:   Citotoxicidad Celular Dependiente de Anticuerpos 
Descriptor Portuguese:   Citotoxicidade Celular Dependente de Anticorpos 
Synonyms English:   ADCC
Antibody Dependent Cell Cytotoxicity
Antibody-Dependent Cell Cytotoxicities
Antibody-Dependent Cell Cytoxicities
Antibody-Dependent Cell Cytoxicity
Cell Cytotoxicities, Antibody-Dependent
Cell Cytotoxicity, Antibody-Dependent
Cell Cytoxicities, Antibody-Dependent
Cell Cytoxicity, Antibody Dependent
Cell Cytoxicity, Antibody-Dependent
Cytotoxicities, Antibody-Dependent Cell
Cytotoxicity, Antibody Dependent Cell
Cytotoxicity, Antibody-Dependent Cell
Cytoxicities, Antibody-Dependent Cell
Cytoxicity, Antibody-Dependent Cell  
Tree Number:   G12.287.070
Definition English:   The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent. 
History Note English:   78 
Allowable Qualifiers English:  
DE drug effects ES ethics
GE genetics IM immunology
PH physiology RE radiation effects
Record Number:   925 
Unique Identifier:   D000920 

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