Search on: ANTIMICROBIAL CATIONIC PEPTIDES 
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Descriptor English:   Antimicrobial Cationic Peptides 
Descriptor Spanish:   Péptidos Catiónicos Antimicrobianos 
Descriptor Portuguese:   Peptídeos Catiônicos Antimicrobianos 
Synonyms English:   Amphipathic Cationic Antimicrobial Peptides
Antimicrobial Peptides, Cationic
Cationic Antimicrobial Peptides
Cationic Peptides, Antimicrobial
Cationic Proteins, Microbicidal
Defense Peptides, Host
Host Defense Peptides
Microbicidal Cationic Proteins
Peptides, Antimicrobial Cationic
Peptides, Cationic Antimicrobial
Peptides, Host Defense
Proteins, Microbicidal Cationic  
Tree Number:   D12.644.050
D12.776.543.695.054
Definition English:   Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane. 
Pharmacological Action:   Anti-Infective Agents
 
See Related English:   Blood Bactericidal Activity
 
History Note English:   2001; use ANTIMICROBIAL CATIONIC PEPTIDES (NM) to search MICROBICIDAL CATIONIC PROTEINS 1981-2000 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   35329 
Unique Identifier:   D023181 

Occurrence in VHL:
 
LILACS    
MEDLINE    
BBO    
MedCarib    
IBECS    

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