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Descriptor English: Arylsulfotransferase
Descriptor Spanish: Arilsulfotransferasa
Descriptor arilsulfotransferasa
Entry term(s) fenol sulfotransferasa
Scope note: Sulfotransferasa que cataliza la sulfatación de un fenol en presencia de 3'-fosfoadenililsulfato como donador de sulfato dando lugar a un arilsulfato y adenosina 3,5'-bifosfato. Ciertos compuestos aromáticos pueden actuar como aceptores; sin embargo, las hidroxilaminas orgánicas no son sustratos. La conjugación del sulfato por esta enzima es una vía importante para la biotransformación de las fármacos fenólicos y catecólicos, así como de neurotransmisores. EC 2.8.2.1.
Descriptor Portuguese: Arilsulfotransferase
Descriptor French: Arylsulfotransferase
Entry term(s): Acetaminophen Sulphotransferase
Aryl Sulfotransferase
Catecholamine Sulfotransferase A
Catecholamine Sulfotransferase B
Dopamine Sulfotransferase
Flavonoid Sulfotransferase
Phenol Sulfokinase
Phenol Sulfotransferase
Phenol Sulfotransferase M
Phenol Sulfotransferase P
Phenolsulfokinase
Phenolsulfotransferase P
Sulfokinase
Sulfotransferase A, Catecholamine
Sulfotransferase B, Catecholamine
Sulfotransferase M, Phenol
Sulfotransferase P, Phenol
Sulfotransferase, Aryl
Sulfotransferase, Dopamine
Sulfotransferase, Flavonoid
Sulfotransferase, Phenol
Sulphotransferase, Acetaminophen
Tree number(s): D08.811.913.817.400.300
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015239
Scope note: A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 2.8.2.1
CAS Type 1 Name: 3'-Phosphoadenylylsulfate:phenol sulfotransferase
Previous Indexing: Sulfurtransferases (1972-1988)
Transferases (1966-1971)
Public MeSH Note: 89
History Note: 89
DeCS ID: 23563
Unique ID: D015239
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/14
Revision Date: 2003/07/09
Arylsulfotransferase - Preferred
Concept UI M0023420
Scope note A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.
Preferred term Arylsulfotransferase
Entry term(s) Aryl Sulfotransferase
Phenol Sulfokinase
Phenol Sulfotransferase
Phenolsulfokinase
Sulfokinase
Sulfotransferase, Aryl
Sulfotransferase, Phenol
Flavonoid Sulfotransferase - Narrower
Concept UI M0023424
Preferred term Flavonoid Sulfotransferase
Entry term(s) Sulfotransferase, Flavonoid
Phenol Sulfotransferase M - Narrower
Concept UI M0023425
Preferred term Phenol Sulfotransferase M
Entry term(s) Sulfotransferase M, Phenol
Catecholamine Sulfotransferase B - Narrower
Concept UI M0023422
Preferred term Catecholamine Sulfotransferase B
Entry term(s) Sulfotransferase B, Catecholamine
Acetaminophen Sulphotransferase - Narrower
Concept UI M0023427
Preferred term Acetaminophen Sulphotransferase
Entry term(s) Sulphotransferase, Acetaminophen
Catecholamine Sulfotransferase A - Narrower
Concept UI M0023421
Preferred term Catecholamine Sulfotransferase A
Entry term(s) Sulfotransferase A, Catecholamine
Dopamine Sulfotransferase - Narrower
Concept UI M0023423
Preferred term Dopamine Sulfotransferase
Entry term(s) Sulfotransferase, Dopamine
Phenolsulfotransferase P - Narrower
Concept UI M0023426
Preferred term Phenolsulfotransferase P
Entry term(s) Phenol Sulfotransferase P
Sulfotransferase P, Phenol



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