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Descriptor English: Atorvastatin
Descriptor Spanish: Atorvastatina
Descriptor atorvastatina
Entry term(s) CI 981
CI-981
CI981
Lipitor
Liptonorm
atorvastatina cálcica
atorvastatina cálcica anhidra
atorvastatina cálcica hidratada
atorvastatina cálcica trihidratada
hidrato de atorvastatina cálcica
sal cálcica de atorvastatina
ácido (3R,5R)-7-(2-(4-fluorofenil)-5-isopropil-3-fenil-4-(fenilcarbamoil)-1H-pirrol-1-il)-3,5-dihidroxiheptanoico
Scope note: Derivado del pirrol y ácido heptanoico, INHIBIDOR DE HIDROXIMETILGLUTARIL-COA REDUCTASAS (estatina) y ANTICOLESTEROLÉMICO que se utiliza en el tratamiento de HIPERLIPIDEMIAS para reducir los niveles séricos de LDL-COLESTEROL, APOLIPOPROTEÍNAS B y TRIGLICÉRIDOS y para aumentar los niveles séricos de HDL-COLESTEROL y prevenir las ENFERMEDADES CARDIOVASCULARES en pacientes con múltiples factores de riesgo.
Descriptor Portuguese: Atorvastatina
Descriptor French: Atorvastatine
Entry term(s): (3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
Atorvastatin Calcium
Atorvastatin Calcium Anhydrous
Atorvastatin Calcium Hydrate
Atorvastatin Calcium Trihydrate
Atorvastatin, Calcium Salt
CI 981
CI-981
CI981
Lipitor
Liptonorm
Tree number(s): D03.383.129.578.075
D10.251.450.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D000069059
Scope note: A pyrrole and heptanoic acid derivative, HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITOR (statin), and ANTICHOLESTEREMIC AGENT that is used to reduce serum levels of LDL-CHOLESTEROL; APOLIPOPROTEIN B; and TRIGLYCERIDES. It is used to increase serum levels of HDL-CHOLESTEROL in the treatment of HYPERLIPIDEMIAS, and for the prevention of CARDIOVASCULAR DISEASES in patients with multiple risk factors.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Anticholesteremic Agents
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Registry Number: A0JWA85V8F
Public MeSH Note: 2019; see ATORVASTATIN CALCIUM 2016-2018; ATORVASTATIN CALCIUM was indexed under HEPTANOIC ACIDS and PYRROLES 1990-2015
History Note: 2019 (1990)
DeCS ID: 55918
Unique ID: D000069059
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 2016/01/01
Date of Entry: 2015/07/10
Revision Date: 2018/07/02
Atorvastatin - Preferred
Concept UI M0179294
Scope note A pyrrole and heptanoic acid derivative, HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITOR (statin), and ANTICHOLESTEREMIC AGENT that is used to reduce serum levels of LDL-CHOLESTEROL; APOLIPOPROTEIN B; and TRIGLYCERIDES. It is used to increase serum levels of HDL-CHOLESTEROL in the treatment of HYPERLIPIDEMIAS, and for the prevention of CARDIOVASCULAR DISEASES in patients with multiple risk factors.
Preferred term Atorvastatin
Entry term(s) (3R,5R)-7-(2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoic acid
Atorvastatin Calcium - Narrower
Concept UI M0324841
Preferred term Atorvastatin Calcium
Entry term(s) Atorvastatin, Calcium Salt
Liptonorm - Narrower
Concept UI M000604589
Preferred term Liptonorm
Lipitor - Narrower
Concept UI M0179293
Preferred term Lipitor
Atorvastatin Calcium Hydrate - Related but not broader or narrower
Concept UI M000638387
Preferred term Atorvastatin Calcium Hydrate
Atorvastatin Calcium Anhydrous - Narrower
Concept UI M0589476
Preferred term Atorvastatin Calcium Anhydrous
CI 981 - Narrower
Concept UI M0179290
Preferred term CI 981
Entry term(s) CI-981
CI981
Atorvastatin Calcium Trihydrate - Narrower
Concept UI M000642807
Preferred term Atorvastatin Calcium Trihydrate



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