Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   Aurora Kinase A 
Descriptor Spanish:   Aurora Quinasa A 
Descriptor Portuguese:   Aurora Quinase A 
Synonyms English:   AURKA
AURORA2 Protein
Aurora A Kinase
Aurora A Kinases
Aurora Kinases A
Aurora-A Kinase
AuroraA Kinase
BTAK Protein
Breast Tumor Amplified Kinase
Breast-Tumor-Amplified Kinase
STK15 Kinase
Serine Threonine Protein Kinase 15
Serine-Threonine Protein Kinase 15  
Tree Number:   D08.811.913.696.620.682.700.103.500
Definition English:   An aurora kinase that localizes to the CENTROSOME during MITOSIS and is involved in centrosome regulation and formation of the MITOTIC SPINDLE. Aurora A overexpression in many malignant tumor types suggests that it may be directly involved in NEOPLASTIC CELL TRANSFORMATION. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   55301 
Unique Identifier:   D064096 

Occurrence in VHL: