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Descriptor English: Azathioprine
Descriptor Spanish: Azatioprina
Descriptor azatioprina
Scope note: Agente inmunosupresor que se utiliza, en combinación con ciclofosfamida e hidrocloroquina, en el tratamiento de la artritis reumatoide. De acuerdo con el Cuarto Informe Anual sobre Carcinógenos (NTP 85-002, 1985), esta sustancia ha sido considerada como cancerígena. (Merck Index, 11th ed)
Descriptor Portuguese: Azatioprina
Descriptor French: Azathioprine
Entry term(s): Azathioprine Sodium
Azathioprine Sodium Salt
Azathioprine Sulfate
Azothioprine
Immuran
Imuran
Imurel
Sodium, Azathioprine
Tree number(s): D02.886.759.111
D03.633.100.759.570.090
D13.570.900.111
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D001379
Scope note: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antimetabolites
Antimetabolites, Antineoplastic
Immunosuppressive Agents
Antirheumatic Agents
Registry Number: MRK240IY2L
CAS Type 1 Name: 1H-Purine, 6-((1-methyl-4-nitro-1H-imidazol-5-yl)thio)-
Public MeSH Note: 66
History Note: 66(64)
DeCS ID: 1394
Unique ID: D001379
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2018/07/05
Azathioprine - Preferred
Concept UI M0002065
Scope note An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
Preferred term Azathioprine
Entry term(s) Azothioprine
Imurel - Narrower
Concept UI M0002067
Preferred term Imurel
Imuran - Narrower
Concept UI M0002066
Preferred term Imuran
Entry term(s) Immuran
Azathioprine Sodium - Narrower
Concept UI M0331325
Preferred term Azathioprine Sodium
Entry term(s) Azathioprine Sodium Salt
Sodium, Azathioprine
Azathioprine Sulfate - Narrower
Concept UI M0331324
Preferred term Azathioprine Sulfate



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