| Descriptor English: | Azauridine | ||||
| Descriptor Spanish: |
Azauridina
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| Descriptor Portuguese: | Azauridina | ||||
| Descriptor French: | 6-Azauridine | ||||
| Entry term(s): |
2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 6 Azauridine 6-Azauridine |
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| Tree number(s): |
D02.145.451 D03.383.742.680.852.176 D13.570.685.852.176 D13.570.800.892.176 |
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| RDF Unique Identifier: | https://id.nlm.nih.gov/mesh/D001380 | ||||
| Scope note: | A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic. |
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| Allowable Qualifiers: |
AA analogs & derivatives AD administration & dosage AE adverse effects AG agonists AI antagonists & inhibitors AN analysis BL blood CF cerebrospinal fluid CH chemistry CL classification CS chemical synthesis EC economics HI history IM immunology IP isolation & purification ME metabolism PD pharmacology PK pharmacokinetics PO poisoning RE radiation effects SD supply & distribution ST standards TO toxicity TU therapeutic use UR urine |
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| Pharm Action: |
Antimetabolites, Antineoplastic Dermatologic Agents |
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| Registry Number: | 7BVB29RCPR | ||||
| CAS Type 1 Name: | 1,2,4-Triazine-3,5(2H,4H)-dione, 2-beta-D-ribofuranosyl- | ||||
| Previous Indexing: |
Antimetabolites (1966-1971) Uridine (1966-1971) |
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| Public MeSH Note: | 73 |
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| History Note: | 73(72) |
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| DeCS ID: | 1396 | ||||
| Unique ID: | D001380 | ||||
| Documents indexed in the Virtual Health Library (VHL): | Click here to access the VHL documents | ||||
| Date Established: | 1973/01/01 | ||||
| Date of Entry: | 1999/01/01 | ||||
| Revision Date: | 2016/05/27 |
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CHEMICALS AND DRUGS
Organic Chemicals [D02]Organic Chemicals -
CHEMICALS AND DRUGS
Heterocyclic Compounds [D03]Heterocyclic Compounds
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Azauridine
- Preferred
| Concept UI |
M0002068 |
| Scope note | A triazine nucleoside used as an antineoplastic antimetabolite. It interferes with pyrimidine biosynthesis thereby preventing formation of cellular nucleic acids. As the triacetate, it is also effective as an antipsoriatic. |
| Preferred term | Azauridine |
| Entry term(s) |
2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 6 Azauridine 6-Azauridine |
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