Search on: BIGUANIDES 
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Descriptor English:   Biguanides 
Descriptor Spanish:   Biguanidas 
Descriptor Portuguese:   Biguanidas 
Tree Number:   D02.078.370.141
Definition English:   Derivatives of biguanide (the structure formula HN(C(NH)NH2)2) that are primarily used as oral HYPOGLYCEMIC AGENTS for the treatment of DIABETES MELLITUS, TYPE 2 and PREDIABETES. 
History Note English:   66(65) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   1670 
Unique Identifier:   D001645 

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