Search on: BREFELDIN A 
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Descriptor English:   Brefeldin A 
Descriptor Spanish:   Brefeldino A 
Descriptor Portuguese:   Brefeldina A 
Synonyms English:   Ascotoxin
NSC 89671
Tree Number:   D02.540.576.500.875
Definition English:   A fungal metabolite which is a macrocyclic lactone exhibiting a wide range of antibiotic activity. 
Pharmacological Action:   Anti-Bacterial Agents
Antifungal Agents
Antiviral Agents
Protein Synthesis Inhibitors
History Note English:   99; use BREFELDIN A (NM) 1980-98 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   33808 
Unique Identifier:   D020126 

Occurrence in VHL: