Search on: CD40 ANTIGENS 
Descriptors Found: 1
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Descriptor English:   CD40 Antigens 
Descriptor Spanish:   Antígenos CD40 
Descriptor Portuguese:   Antígenos CD40 
Synonyms English:   Antigen, CD40
Antigen, CDw40
Antigens, CD40
CD40 Antigen
CDw40 Antigen
Receptor, TNFRSF5
TNFRSF5 Receptor
Tumor Necrosis Factor Receptor Superfamily, Member 5  
Tree Number:   D12.776.543.750.705.852.760.097
Definition English:   Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS. 
See Related English:   CD40 Ligand
History Note English:   2018 (1988) 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   32846 
Unique Identifier:   D019013 

Occurrence in VHL: