Descriptors Found: 1
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Descriptor English:   Chloramphenicol O-Acetyltransferase 
Descriptor Spanish:   Cloranfenicol O-Acetiltransferasa 
Descriptor Portuguese:   Cloranfenicol O-Acetiltransferase 
Synonyms English:   Acetyltransferase, Chloramphenicol
CAT Enzyme
Chloramphenicol Acetyltransferase
Chloramphenicol O Acetyltransferase
Chloramphenicol Transacetylase
Enzyme, CAT
O-Acetyltransferase, Chloramphenicol
Transacetylase, Chloramphenicol  
Tree Number:   D08.811.913.050.134.170
Definition English:   An enzyme that catalyzes the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. EC 
See Related English:   Chloramphenicol Resistance
History Note English:   98(89) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   23584 
Unique Identifier:   D015500 

Occurrence in VHL: