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Descriptor English: Chymotrypsin
Descriptor Spanish: Quimotripsina
Descriptor quimotripsina
Entry term(s) alfa-quimiotripsina
alfa-quimotripsina
quimiotripsina
Scope note: Serina endopeptidasa segregada por el páncreas como su zimógeno, el QUIMOTRIPSINÓGENO, y transportada en el jugo pancreático hasta el duodeno, donde es activada por la TRIPSINA. Escinde selectivamente aminoácidos aromáticos en el lado carboxílico.
Descriptor Portuguese: Quimotripsina
Descriptor French: Chymotrypsine
Entry term(s): Alpha-Chymotrypsin Choay
Alphacutanée
Avazyme
Tree number(s): D08.811.277.656.300.760.176
D08.811.277.656.959.350.176
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D002918
Scope note: A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.
Annotation: /antag: consider also ALPHA 1-ANTICHYMOTRYPSIN
Allowable Qualifiers: AD administration & dosage
AE adverse effects
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
DE drug effects
DF deficiency
EC economics
GE genetics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PH physiology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UL ultrastructure
UR urine
Registry Number: EC 3.4.21.1
CAS Type 1 Name: Chymotrypsin
DeCS ID: 23198
Unique ID: D002918
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1966/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/01
Chymotrypsin - Preferred
Concept UI M0004462
Scope note A serine endopeptidase secreted by the pancreas as its zymogen, CHYMOTRYPSINOGEN and carried in the pancreatic juice to the duodenum where it is activated by TRYPSIN. It selectively cleaves aromatic amino acids on the carboxyl side.
Preferred term Chymotrypsin
Alphacutanée - Narrower
Concept UI M0478343
Preferred term Alphacutanée
Alpha-Chymotrypsin Choay - Narrower
Concept UI M0478344
Preferred term Alpha-Chymotrypsin Choay
Avazyme - Narrower
Concept UI M0478342
Preferred term Avazyme



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