Search on: COSTIMULATORY AND INHIBITORY T-CELL RECEPTORS 
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Descriptor English:   Costimulatory and Inhibitory T-Cell Receptors 
Descriptor Spanish:   Receptores Coestimuladores e Inhibidores de Linfocitos T 
Descriptor Portuguese:   Receptores Coestimuladores e Inibidores de Linfócitos T 
Synonyms English:   Costimulatory T Cell Receptors
Costimulatory T Lymphocyte Receptors
Costimulatory T-Cell Receptors
Costimulatory T-Lymphocyte Receptors
Costimulatory and Inhibitory T Cell Receptors
Costimulatory and Inhibitory T Lymphocyte Receptors
Costimulatory and Inhibitory T-Lymphocyte Receptors
Inhibitory T Cell Receptors
Inhibitory T Lymphocyte Receptors
Inhibitory T-Cell Receptors
Inhibitory T-Lymphocyte Receptors
Receptors, Costimulatory T-Cell
Receptors, Costimulatory T-Lymphocyte
Receptors, Costimulatory and Inhibitory, T-Lymphocyte
Receptors, Costimulatory, T-Lymphocyte
Receptors, Inhibitory T-Cell
Receptors, Inhibitory T-Lymphocyte
Receptors, Inhibitory, T-Cell
T-Cell Receptors, Costimulatory
T-Cell Receptors, Inhibitory
T-Lymphocyte Receptors, Costimulatory
T-Lymphocyte Receptors, Inhibitory  
Tree Number:   D12.776.543.750.705.222
Definition English:   A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE. 
History Note English:   2012 
Allowable Qualifiers English:  
AD administration & dosage AG agonists
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CH chemistry CL classification
DF deficiency DE drug effects
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PH physiology
RE radiation effects TU therapeutic use
UL ultrastructure  
Record Number:   54633 
Unique Identifier:   D061025 

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