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Descriptor English: Cromakalim
Descriptor Spanish: Cromakalim
Descriptor cromakalim
Entry term(s) levcromakalim
Scope note: Vasodilatador que abre los canales de potasio y que ha sido investigado en el manejo de la hipertensión. Asimismo, se ha probado en pacientes con asma. (Martindale, The Extra Pharmacopoeia, 30th ed, p352)
Descriptor Portuguese: Cromakalim
Descriptor French: Cromakalim
Entry term(s): BRL 38226
BRL 38227
BRL-34915
BRL-38226
BRL-38227
BRL38226
BRL38227
Cromakalim, (3R-cis)-Isomer
Cromakalim, (3R-trans)-Isomer
Cromakalim, (3S-cis)-Isomer
Cromakalim, (3S-trans)-Isomer
Cromakalim, (trans)-Isomer
Lemakalim
Levcromakalim
Tree number(s): D03.383.129.578.150
D03.383.663.283.455
D03.633.100.150.455
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D019806
Scope note: A potassium-channel opening vasodilator that has been investigated in the management of hypertension. It has also been tried in patients with asthma. (Martindale, The Extra Pharmacopoeia, 30th ed, p352)
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antihypertensive Agents
Bronchodilator Agents
Parasympatholytics
Vasodilator Agents
Registry Number: 0G4X367WA3
CAS Type 1 Name: 2H-1-Benzopyran-6-carbonitrile, 3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-, trans-(+-)-
Previous Indexing: Benzopyrans (1986-1997)
Pyrroles (1986-1997)
Public MeSH Note: 98; CROMAKALIM was indexed under BENZOPYRANS & PYRROLES 1986-97
History Note: 98; use CROMAKALIM (NM) 1986-97
DeCS ID: 33628
Unique ID: D019806
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1998/01/01
Date of Entry: 1997/06/20
Revision Date: 2016/05/28
Cromakalim - Preferred
Concept UI M0029396
Scope note A potassium-channel opening vasodilator that has been investigated in the management of hypertension. It has also been tried in patients with asthma. (Martindale, The Extra Pharmacopoeia, 30th ed, p352)
Preferred term Cromakalim
BRL-34915 - Narrower
Concept UI M0372959
Preferred term BRL-34915
BRL-38226 - Narrower
Concept UI M0029397
Preferred term BRL-38226
Entry term(s) BRL 38226
BRL38226
Cromakalim, (3R-cis)-Isomer - Narrower
Concept UI M0329128
Preferred term Cromakalim, (3R-cis)-Isomer
Cromakalim, (3S-cis)-Isomer - Narrower
Concept UI M0329129
Preferred term Cromakalim, (3S-cis)-Isomer
Cromakalim, (trans)-Isomer - Narrower
Concept UI M0329131
Preferred term Cromakalim, (trans)-Isomer
Lemakalim - Narrower
Concept UI M0353590
Preferred term Lemakalim
Levcromakalim - Narrower
Concept UI M0329132
Preferred term Levcromakalim
Entry term(s) Cromakalim, (3S-trans)-Isomer
BRL-38227 - Narrower
Concept UI M0029398
Preferred term BRL-38227
Entry term(s) BRL 38227
BRL38227
Cromakalim, (3R-trans)-Isomer - Narrower
Concept UI M0329133
Preferred term Cromakalim, (3R-trans)-Isomer



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