Search on: DAPSONE 
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Descriptor English:   Dapsone 
Descriptor Spanish:   Dapsona 
Descriptor Portuguese:   Dapsona 
Synonyms English:   4,4' Diaminophenyl Sulfone
4,4'-Diaminophenyl Sulfone
Avlosulfone
DADPS
Dapsoderm-X
Dapson-Fatol
Diaminodiphenylsulfone
Diaphenylsulfone
Disulone
Sulfona
Sulfone, 4,4'-Diaminophenyl
Sulfonyldianiline  
Tree Number:   D02.886.590.263
Definition English:   A sulfone active against a wide range of bacteria but mainly employed for its actions against MYCOBACTERIUM LEPRAE. Its mechanism of action is probably similar to that of the SULFONAMIDES which involves inhibition of folic acid synthesis in susceptible organisms. It is also used with PYRIMETHAMINE in the treatment of malaria. (From Martindale, The Extra Pharmacopoeia, 30th ed, p157-8) 
Pharmacological Action:   Anti-Infective Agents
Antimalarials
Folic Acid Antagonists
Leprostatic Agents
 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   3641 
Unique Identifier:   D003622 

Occurrence in VHL:
 
LILACS    
MEDLINE    
BBO    
BDENF    
MedCarib    
IBECS    

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