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Descriptor English:   Deoxyribonucleases, Type III Site-Specific 
Descriptor Spanish:   Desoxirribonucleasas de Localización Especificada Tipo III 
Descriptor Portuguese:   Desoxirribonucleases de Sítio Específico do Tipo III 
Synonyms English:   DNA Restriction Enzymes, Type III
DNase, Site Specific, Type III
DNase, Site-Specific, Type III
Deoxyribonucleases, Type III Site Specific
Deoxyribonucleases, Type III, Site Specific
Deoxyribonucleases, Type III, Site-Specific
Restriction Endonucleases, Type III
Site Specific DNase, Type III
Site-Specific DNase, Type III
Type III Restriction Enzymes
Type III Site Specific DNase
Type III Site Specific Deoxyribonucleases
Type III Site-Specific DNase
Type III Site-Specific Deoxyribonucleases  
Tree Number:   D08.811.150.280.270
Definition English:   Enzyme systems composed of two subunits and requiring ATP and magnesium for endonucleolytic activity; they do not function as ATPases. They exist as complexes with modification methylases of similar specificity listed under EC or EC The systems recognize specific short DNA sequences and cleave a short distance, about 24 to 27 bases, away from the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 
History Note English:   89 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   23604 
Unique Identifier:   D015263 

Occurrence in VHL: