Descriptors Found: 1
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 1 / 1 DeCS     
Descriptor English:   Dopamine Antagonists 
Descriptor Spanish:   Antagonistas de Dopamina 
Descriptor Portuguese:   Antagonistas de Dopamina 
Synonyms English:   Antagonists, Dopamine
Antagonists, Dopamine Receptor
Antagonists, Dopaminergic
Blockers, Dopamine
Dopamine Blockers
Dopamine Receptor Antagonists
Dopaminergic Antagonists
Receptor Antagonists, Dopamine  
Tree Number:   D27.505.519.625.150.175
Definition English:   Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. 
History Note English:   95 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   32275 
Unique Identifier:   D018492 

Occurrence in VHL: