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Descriptor English: Epirubicin
Descriptor Spanish: Epirrubicina
Descriptor epirrubicina
Entry term(s) 4'-epiadriamicina
4'-epidoxorrubicina
Scope note: Antraciclina epi-isómero 4' de la doxorrubicina. El compuesto ejerce sus efectos antitumorales por interferencia en la síntesis y función del ADN.
Descriptor Portuguese: Epirubicina
Descriptor French: Épirubicine
Entry term(s): 4' Epi Adriamycin
4' Epi DXR
4' Epi Doxorubicin
4' Epiadriamycin
4' Epidoxorubicin
4'-Epi-Adriamycin
4'-Epi-DXR
4'-Epi-Doxorubicin
4'-Epiadriamycin
4'-Epidoxorubicin
EPI cell
EPI-cell
EPIcell
Ellence
Epilem
Epirubicin Hydrochloride
Farmorubicin
Farmorubicina
Farmorubicine
Hydrochloride, Epirubicin
IMI 28
IMI-28
IMI28
NSC 256942
NSC-256942
NSC256942
Pharmorubicin
Tree number(s): D02.455.426.559.847.562.050.200.175.200
D04.615.562.050.200.175.200
D09.408.051.059.200.175.200
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D015251
Scope note: An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BI biosynthesis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Antibiotics, Antineoplastic
Topoisomerase II Inhibitors
Registry Number: 3Z8479ZZ5X
CAS Type 1 Name: 5,12-Naphthacenedione, 10-((3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-, (8S-cis)-
Previous Indexing: Doxorubicin (1973-1988)
Public MeSH Note: 89
History Note: 89
DeCS ID: 23628
Unique ID: D015251
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1989/01/01
Date of Entry: 1988/05/16
Revision Date: 2016/07/01
Epirubicin - Preferred
Concept UI M0023488
Scope note An anthracycline which is the 4'-epi-isomer of doxorubicin. The compound exerts its antitumor effects by interference with the synthesis and function of DNA.
Preferred term Epirubicin
Entry term(s) 4' Epi Adriamycin
4' Epi DXR
4' Epi Doxorubicin
4' Epiadriamycin
4' Epidoxorubicin
4'-Epi-Adriamycin
4'-Epi-DXR
4'-Epi-Doxorubicin
4'-Epiadriamycin
4'-Epidoxorubicin
EPI-cell - Narrower
Concept UI M0485316
Preferred term EPI-cell
Entry term(s) EPI cell
EPIcell
Epilem - Narrower
Concept UI M0485315
Preferred term Epilem
Farmorubicina - Narrower
Concept UI M0485317
Preferred term Farmorubicina
IMI-28 - Narrower
Concept UI M0350665
Preferred term IMI-28
Entry term(s) IMI 28
IMI28
NSC-256942 - Narrower
Concept UI M0350669
Preferred term NSC-256942
Entry term(s) NSC 256942
NSC256942
Ellence - Narrower
Concept UI M0023489
Preferred term Ellence
Entry term(s) Farmorubicin
Farmorubicine
Pharmorubicin
Epirubicin Hydrochloride - Narrower
Concept UI M0329520
Preferred term Epirubicin Hydrochloride
Entry term(s) Hydrochloride, Epirubicin



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