Search on: ERYTHROMYCIN ETHYLSUCCINATE 
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Descriptor English:   Erythromycin Ethylsuccinate 
Descriptor Spanish:   Etilsuccinato de Eritromicina 
Descriptor Portuguese:   Etilsuccinato de Eritromicina 
Synonyms English:   E-Mycin E
EMycin E
EryPed
Erythroped
Ethyl Succinate, Eyrthromycin
Ethylsuccinate, Erythromycin
Eyrthromycin Ethyl Succinate
Monomycin
Pediamycin
Succinate, Eyrthromycin Ethyl
Wyamycin E  
Tree Number:   D02.540.576.500.992.260
Definition English:   A macrolide antibiotic, produced by Streptomyces erythreus. This compound is an ester of erythromycin base and succinic acid. It acts primarily as a bacteriostatic agent. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins. 
Pharmacological Action:   Anti-Bacterial Agents
Enzyme Inhibitors
Gastrointestinal Agents
Protein Synthesis Inhibitors
 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   24629 
Unique Identifier:   D015643 

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