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Descriptor English:   Extracellular Matrix Proteins 
Descriptor Spanish:   Proteínas de la Matriz Extracelular 
Descriptor Portuguese:   Proteínas da Matriz Extracelular 
Synonyms English:   Matrix Proteins, Extracellular
Proteins, Extracellular Matrix  
Tree Number:   D12.776.860.300
Definition English:   Macromolecular organic compounds that contain carbon, hydrogen, oxygen, nitrogen, and usually, sulfur. These macromolecules (proteins) form an intricate meshwork in which cells are embedded to construct tissues. Variations in the relative types of macromolecules and their organization determine the type of extracellular matrix, each adapted to the functional requirements of the tissue. The two main classes of macromolecules that form the extracellular matrix are: glycosaminoglycans, usually linked to proteins (proteoglycans), and fibrous proteins (e.g., COLLAGEN; ELASTIN; FIBRONECTINS; and LAMININ). 
Indexing Annotation English:   /drug eff /ultrastruct permitted
See Related English:   Extracellular Traps
Receptors, Cytoadhesin
History Note English:   91 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   28931 
Unique Identifier:   D016326 

Occurrence in VHL: