Search on: FACTOR XIA 
Descriptors Found: 1
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Descriptor English:   Factor XIa 
Descriptor Spanish:   Factor XIa 
Descriptor Portuguese:   Fator XIa 
Synonyms English:   Activated Factor XI
Blood Coagulation Factor XI, Activated
Coagulation Factor XIa
Contact Activation Product
Factor 11A
Factor Eleven A
Factor XI, Activated
Factor XIa, Coagulation  
Tree Number:   D08.811.277.656.300.760.320
D08.811.277.656.959.350.320
D12.776.124.125.425.320
D23.119.425.320
Definition English:   Activated form of factor XI. In the intrinsic pathway, Factor XI is activated to XIa by factor XIIa in the presence of cofactor HMWK; (HIGH MOLECULAR WEIGHT KININOGEN). Factor XIa then activates factor IX to factor IXa in the presence of calcium. 
Indexing Annotation English:   /defic = FACTOR XI DEFICIENCY
See Related English:   Coagulants
 
History Note English:   90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   24647 
Unique Identifier:   D015945 

Occurrence in VHL:
 
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