Search on: FENCLONINE 
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Descriptor English:   Fenclonine 
Descriptor Spanish:   Fenclonina 
Descriptor Portuguese:   Fenclonina 
Synonyms English:   CP-10,188
Fenclonine (L)-Isomer
Fenclonine Hydrobromide
Fenclonine Hydrochloride
Fenclonine, (D)-Isomer
Hydrobromide, Fenclonine
Hydrochloride, Fenclonine
para Chlorophenylalanine
Tree Number:   D12.
Definition English:   A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin. 
Pharmacological Action:   Enzyme Inhibitors
Serotonin Antagonists
History Note English:   93(71) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   30927 
Unique Identifier:   D010134 

Occurrence in VHL: