Search on: FINGOLIMOD HYDROCHLORIDE 
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Descriptor English:   Fingolimod Hydrochloride 
Descriptor Spanish:   Clorhidrato de Fingolimod 
Descriptor Portuguese:   Cloridrato de Fingolimode 
Synonyms English:   2-Amino-2-(2-(4-octylphenyl)ethyl)-1,3-propanediol hydrochloride
FTY 720
FTY-720
FTY720
Fingolimod
Gilenia
Gilenya
Hydrochloride, Fingolimod  
Tree Number:   D02.033.100.700.350
D02.033.455.706.431
D02.092.063.700.350
Definition English:   A sphingosine-derivative and IMMUNOSUPPRESSIVE AGENT that blocks the migration and homing of LYMPHOCYTES to the CENTRAL NERVOUS SYSTEM through its action on SPHINGOSINE 1-PHOSPHATE RECEPTORS. It is used in the treatment of MULTIPLE SCLEROSIS. 
Pharmacological Action:   Immunosuppressive Agents
 
History Note English:   2016 (1996) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AA analogs & derivatives
AN analysis AI antagonists & inhibitors
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification EC economics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UR urine  
Record Number:   55866 
Unique Identifier:   D000068876 

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