Search on: GLUCOSYLCERAMIDASE 
Descriptors Found: 1
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Descriptor English:   Glucosylceramidase 
Descriptor Spanish:   Glucosilceramidasa 
Descriptor Portuguese:   Glucosilceramidase 
Synonyms English:   Acid beta Glucosidase
Acid beta-Glucosidase
Ceramidase, Glucosyl
Glucocerebrosidase
Glucocerebroside beta Glucosidase
Glucocerebroside beta-Glucosidase
Glucosyl Ceramidase
Glucosyl Hydrolase, Glucosylsphingosine
Glucosylceramide beta Glucosidase
Glucosylceramide beta-Glucosidase
Glucosylsphingosine Glucosyl Hydrolase
Hydrolase, Glucosylsphingosine Glucosyl
beta Glucocerebrosidase
beta-Glucocerebrosidase
beta-Glucosidase, Acid
beta-Glucosidase, Glucocerebroside
beta-Glucosidase, Glucosylceramide  
Tree Number:   D08.811.277.450.420.412
Definition English:   A glycosidase that hydrolyzes a glucosylceramide to yield free ceramide plus glucose. Deficiency of this enzyme leads to abnormally high concentrations of glucosylceramide in the brain in GAUCHER DISEASE. EC 3.2.1.45. 
Indexing Annotation English:   /defic: consider also GAUCHER DISEASE
See Related English:   Gaucher Disease
 
History Note English:   91(75); was see under GLUCOSIDASES 1975-90 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   6107 
Unique Identifier:   D005962 

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