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Descriptor English:   Hexamethonium 
Descriptor Spanish:   Hexametonio 
Descriptor Portuguese:   Hexametônio 
Synonyms English:   Bitartrate, Hexamethonium
Bromide, Hexamethonium
Chloride, Hexamethonium
Dibromide Dihydrate, Hexamethonium
Dibromide, Hexamethonium
Dichloride Dihydrate, Hexamethonium
Dihydrate, Hexamethonium Dibromide
Dihydrate, Hexamethonium Dichloride
Dihydroxide, Hexamethonium
Diiodide, Hexamethonium
Dimethylsulfate, Hexamethonium
Diperchlorate, Hexamethonium
Hexamethonium Bitartrate
Hexamethonium Bromide
Hexamethonium Chloride
Hexamethonium Dibromide
Hexamethonium Dibromide Dihydrate
Hexamethonium Dichloride Dihydrate
Hexamethonium Dihydroxide
Hexamethonium Diiodide
Hexamethonium Dimethylsulfate
Hexamethonium Diperchlorate
Hexamethonium Iodide
Hexamethonium Monotartrate
Iodide, Hexamethonium
Monotartrate, Hexamethonium  
Tree Number:   D02.092.877.250.592.400
Definition English:   A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool. 
Pharmacological Action:   Antihypertensive Agents
Ganglionic Blockers
Nicotinic Antagonists
Entry Combination - descr/qualif English:   Hexamethonium/analogs & derivatives use Hexamethonium Compounds
History Note English:   95; was HEXAMETHONIUM (NM) 1980-94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
EC economics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PO poisoning
RE radiation effects ST standards
SD supply & distribution TU therapeutic use
TO toxicity UR urine
Record Number:   32201 
Unique Identifier:   D018738 

Occurrence in VHL: