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Descriptor English: Iloprost
Descriptor Spanish: Iloprost
Descriptor iloprost
Entry term(s) ciloprost
Scope note: Eicosanoide derivado de la vía de la ciclooxigenasa del metabolismo del ácido araquidónico. Es un análogo estable y sintético del EPOPROSTENOL, pero con una semivida más prolongada que el compuesto madre. Sus acciones son similalres a las de la prostaciclina. El compuesto iloprost produce vasodilatación e inhibe la agregación plaquetaria.
Descriptor Portuguese: Iloprosta
Descriptor French: Iloprost
Entry term(s): Ciloprost
Ventavis
ZK 36374
ZK-36374
ZK36374
Tree number(s): D10.251.355.255.550.775.125
D23.469.050.175.725.775.125
D23.469.700.275
RDF Unique Identifier: https://id.nlm.nih.gov/mesh/D016285
Scope note: An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.
Allowable Qualifiers: AA analogs & derivatives
AD administration & dosage
AE adverse effects
AG agonists
AI antagonists & inhibitors
AN analysis
BL blood
CF cerebrospinal fluid
CH chemistry
CL classification
CS chemical synthesis
EC economics
HI history
IM immunology
IP isolation & purification
ME metabolism
PD pharmacology
PK pharmacokinetics
PO poisoning
RE radiation effects
SD supply & distribution
ST standards
TO toxicity
TU therapeutic use
UR urine
Pharm Action: Platelet Aggregation Inhibitors
Vasodilator Agents
Registry Number: JED5K35YGL
CAS Type 1 Name: Pentanoic acid, 5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene)-
Previous Indexing: Cardiovascular Agents (1979-1990)
Epoprostenol (1978-1990)
Vasodilator Agents (1966-1990)
Public MeSH Note: 91
History Note: 91
DeCS ID: 28988
Unique ID: D016285
Documents indexed in the Virtual Health Library (VHL): Click here to access the VHL documents
Date Established: 1991/01/01
Date of Entry: 1990/05/29
Revision Date: 2016/07/01
Iloprost - Preferred
Concept UI M0024894
Scope note An eicosanoid, derived from the cyclooxygenase pathway of arachidonic acid metabolism. It is a stable and synthetic analog of EPOPROSTENOL, but with a longer half-life than the parent compound. Its actions are similar to prostacyclin. Iloprost produces vasodilation and inhibits platelet aggregation.
Preferred term Iloprost
Entry term(s) Ciloprost
ZK-36374 - Narrower
Concept UI M0351561
Preferred term ZK-36374
Entry term(s) ZK 36374
ZK36374
Ventavis - Narrower
Concept UI M0484562
Preferred term Ventavis



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