Search on: ISLET AMYLOID POLYPEPTIDE 
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Descriptor English:   Islet Amyloid Polypeptide 
Descriptor Spanish:   Polipéptido Amiloide de los Islotes Pancreáticos 
Descriptor Portuguese:   Polipeptídeo Amiloide das Ilhotas Pancreáticas 
Synonyms English:   Amlintide
Amylin
Amylin, Pancreatic
Amyloid Polypeptide, Insulinoma
Amyloid Polypeptide, Islet
IAPP Precursor
IAPP Protein
Insulinoma Amyloid Polypeptide
Insulinoma Amyloid Polypeptide Precursor
Islet Amyloid Polypeptide Precursor
Pancreatic Amylin
Polypeptide, Insulinoma Amyloid
Polypeptide, Islet Amyloid  
Tree Number:   D06.472.699.587.334
D12.644.548.586.234
D12.776.049.407.500
Definition English:   A pancreatic beta-cell hormone that is co-secreted with INSULIN. It displays an anorectic effect on nutrient metabolism by inhibiting gastric acid secretion, gastric emptying and postprandial GLUCAGON secretion. Islet amyloid polypeptide can fold into AMYLOID FIBRILS that have been found as a major constituent of pancreatic AMYLOID DEPOSITS. 
Pharmacological Action:   Appetite Depressants
Amylin Receptor Agonists
 
History Note English:   2011 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   54057 
Unique Identifier:   D058228 

Occurrence in VHL:
 
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